Prostaglandins and model aspects of thrombosis.
نویسنده
چکیده
The possible role of prostaglandins (PGs) in thrombosis was determined by examining their effects in models of thrombosis which included platelet aggregation (in vitro), blood flow (in vivo) and thrombus formation (in vivo). It was found that blood flow and thrombosis can be effectively modulated by the various types of prostaglandins produced by the blood and the vascular tissue.
منابع مشابه
The Role of Nitric Oxide and Prostaglandins in the Effect of Adenosine on Contractility, Heart Rate and Coronary Blood Flow in Guinea Pig Isolated Heart
It is a well-established fact that adenosine and its receptor subtypes (A 1 and A ) are involved in changes of contractility, heart rate and coronary blood flow (CBF) under different circumstances. This study was conducted to evaluate the role of nitric oxide and prostaglandins in development of these changes. For this purpose, Nitro-L-Arginine methyl ester (L-NAME), and indomethacin as inhibit...
متن کاملImaging of Clot by 99mTc-HMPAO Labeled Platelet in Animal Model Induced Thrombosis
99mTc-HMPAO labeled platelet (LP) imaging may integrate thrombosis imaging into routine clinical procedures. In the current study, we assessed the feasibility of the use of 99mTc-HMPAO LP for imaging of small clots in an animal model. Thrombosis was induced by application of FeCl3 solution in the distal part of the inferior vena cava (IVC) of a 6100 g anesthetiz...
متن کاملEvaluation of radiolabeled streptokinase for thrombosis imaging
Introduction: Cardiovascular disease is the major cause of morbidity and mortality in developing and developed countries. Rapid diagnosis of the thrombosis can be an essential step in management of the stroke. Methods: In this work a recently developed radiolabeled streptokinase (STP) tracer was evaluated in an animal thrombotic model using SPECT imaging and biodis...
متن کاملLetter: Intermittent calf compression in prevention of deep venous thrombosis.
Innocent Praecordial Murmurs in Children H. A. Fleming, F.R.C.P ................... 270 Cervical Cone Biopsy and Fertility M. M. Boddington, M.R.C.PATH., and A. I. Spriggs, F.R.C.P ......................... 271 Cervical Injury and Prostaglandins I. L. Craft, M.R.C.O.G., and E. Youssefnejadian, PH.D ............................. 271 Meningococcal Disease R. J. Fallon, F.R.C.PATH.; R. B. McGucken...
متن کاملNeonatal Thrombosis: Incidence and Risk Factors in a Tertiary Care Hospital in Iran
Background: Neonatal thrombosis is one of the most important challenges among patients admitted in Neonatal Intensive Care Unit (NICU), which can lead to an asymptomatic condition, limb loss or even death. This study was performed to determine the incidence and risk factors of neonatal thrombosis in a tertiary care hospital in Tehran, Iran. Material and Methods: In this historical cohort, all n...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Postgraduate medical journal
دوره 53 625 شماره
صفحات -
تاریخ انتشار 1977